06 Juli 2025
| 04:30 |
San Diego FC 
3 - 4
Houston Dynamo 
|
13 Juli 2025
| 03:30 |
Real Salt Lake 
1 - 0
Houston Dynamo
|
17 Juli 2025
| 02:30 |
Houston Dynamo
0 - 3
Vancouver Whitecaps FC 
|
20 Juli 2025
| 02:30 |
Houston Dynamo
1 - 1
Philadelphia Union 
|
10 Augustus 2025
| 02:30 |
Austin FC 
2 - 2
Houston Dynamo
|
18 Augustus 2025
| 03:00 |
Vancouver Whitecaps FC
1 - 1
Houston Dynamo
|
24 Augustus 2025
| 02:30 |
Houston Dynamo
1 - 2
San Jose Earthquakes 
|
31 Augustus 2025
| 02:30 |
St. Louis City SC 
2 - 3
Houston Dynamo
|
07 September 2025
| 02:30 |
Houston Dynamo
1 - 1
Los Angeles Galaxy 
|
14 September 2025
| 03:30 |
Colorado Rapids SC 
2 - 1
Houston Dynamo
|