10 Augustus 2025
| 14:30 |
AFC Ajax 
2 - 0
Telstar 1963 
|
17 Augustus 2025
| 12:15 |
Go Ahead Eagles 
2 - 2
AFC Ajax
|
24 Augustus 2025
| 16:45 |
AFC Ajax
2 - 0
Heracles Almelo 
|
30 Augustus 2025
| 16:30 |
FC Volendam 
1 - 1
AFC Ajax
|
13 September 2025
| 16:30 |
AFC Ajax
3 - 1
PEC Zwolle 
|
17 September 2025
| 21:00 |
AFC Ajax
0 - 2
FC Internazionale Milano 
|
21 September 2025
| 14:30 |
PSV 
2 - 2
AFC Ajax
|
27 September 2025
| 16:30 |
AFC Ajax
2 - 1
NAC Breda 
|
30 September 2025
| 21:00 |
Olympique de Marseille 
4 - 0
AFC Ajax
|
04 Oktober 2025
| 16:30 |
Sparta Rotterdam 
3 - 3
AFC Ajax
|
18 Oktober 2025
| 21:00 |
AFC Ajax
0 - 2
AZ 
|
