23 Augustus 2025
| 15:30 |
Bayer 04 Leverkusen 
1 - 2
TSG 1899 Hoffenheim 
|
30 Augustus 2025
| 15:30 |
TSG 1899 Hoffenheim
1 - 3
Eintracht Frankfurt 
|
13 September 2025
| 15:30 |
1. FC Union Berlin 
2 - 4
TSG 1899 Hoffenheim
|
20 September 2025
| 15:30 |
TSG 1899 Hoffenheim
1 - 4
FC Bayern München 
|
28 September 2025
| 15:30 |
SC Freiburg 
1 - 1
TSG 1899 Hoffenheim
|
03 Oktober 2025
| 20:30 |
TSG 1899 Hoffenheim
0 - 1
1. FC Köln 
|
19 Oktober 2025
| 17:30 |
FC St. Pauli 1910 
0 - 3
TSG 1899 Hoffenheim
|
25 Oktober 2025
| 15:30 |
TSG 1899 Hoffenheim
3 - 1
1. FC Heidenheim 1846 
|
02 November 2025
| 17:30 |
VfL Wolfsburg 
2 - 3
TSG 1899 Hoffenheim
|
08 November 2025
| 15:30 |
TSG 1899 Hoffenheim
3 - 1
RB Leipzig 
|
21 November 2025
| 20:30 |
1. FSV Mainz 05 
1 - 1
TSG 1899 Hoffenheim
|
29 November 2025
| 15:30 |
TSG 1899 Hoffenheim
3 - 0
FC Augsburg 
|
07 December 2025
| 17:30 |
BV Borussia 09 Dortmund 
2 - 0
TSG 1899 Hoffenheim
|
13 December 2025
| 15:30 |
TSG 1899 Hoffenheim
4 - 1
Hamburger SV 
|
20 December 2025
| 15:30 |
VfB Stuttgart 
0 - 0
TSG 1899 Hoffenheim
|