06 Juli 2025
| 01:30 |
FC Cincinnati 
2 - 1
Chicago Fire FC 
|
13 Juli 2025
| 02:30 |
Chicago Fire FC
1 - 2
San Diego FC 
|
17 Juli 2025
| 01:30 |
Atlanta United FC 
2 - 2
Chicago Fire FC
|
20 Juli 2025
| 01:30 |
CF Montréal 
0 - 2
Chicago Fire FC
|
27 Juli 2025
| 02:30 |
Chicago Fire FC
1 - 0
New York Red Bulls 
|
10 Augustus 2025
| 02:30 |
Chicago Fire FC
2 - 2
Los Angeles FC 
|
17 Augustus 2025
| 02:30 |
Chicago Fire FC
3 - 2
St. Louis City SC 
|
24 Augustus 2025
| 01:30 |
Philadelphia Union 
4 - 0
Chicago Fire FC
|
07 September 2025
| 02:30 |
Chicago Fire FC
3 - 2
New England Revolution 
|
14 September 2025
| 02:30 |
Chicago Fire FC
1 - 3
New York City FC 
|